Supplementary materials: Meta-analysis of visual pretreatment for the prevention of emergence delirium in children undergoing ophthalmic surgery

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posted on 2024-05-03, 12:44 authored by Dong She, Zi-Yu Wang, Fei Wu, Yin-Qin Zhang, Qin Ao

These are peer-reviewed supplementary materials for the article 'Meta-analysis of visual pretreatment for the prevention of emergence delirium in children undergoing ophthalmic surgery' published in the Journal of Comparative Effectiveness Research.

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Objective: To evaluate the role of visual pretreatment in preventing emergence delirium in children receiving ophthalmic surgery. Methods: Four randomized controlled trials were identified in four databases, and a meta-analysis was conducted using RevMan 5.3. Results: Themeta-analysis demonstrated a significantly lower incidence of postoperative emergence delirium (risk ratio: 0.39; 95% CI: 0.31–0.49) and propofol rescue (risk ratio: 0.29; 95% CI: 0.13–0.65) but comparable modified Yale Preoperative Anxiety Scale score (mean difference: -3.66; 95% CI: -9.96 to 2.65) and incidence of adverse events in the visual pretreatment group. Conclusion: Visual pretreatment is effective in preventing postoperative emergence delirium in children undergoing ophthalmic surgery without significant adverse effects and can also decrease the incidence of propofol rescue.